Related Experiment Video
Updated: Mar 21, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
Published on: September 4, 2017
Quantitative evaluation of conservatism included in the derivation of clearance level: a case study for major
Michiya Sasaki1, Tatsuki Kimura1
1Biology and Environmental Chemistry Division, Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry, 1646 Abiko, Abiko-shi, Chiba 270-1194, Japan.
Abstract:
Clearance levels, which are estimated by the International Atomic Energy Agency as the activity concentration corresponding to an effective dose of 10 μSv per year, are widely used; however, it has been pointed out that there is a large conservatism in their estimation. In the present study, we have attempted to examine the conservatism included in the derivation of clearance levels by selecting major radionuclides, considering the "factor of conservatism" included in the parameter settings and applying data on the latest statistical information from Japan. As a result, the factor of conservatism for activity concentration corresponding to an effective dose of 10 μSv per year was evaluated to be approximately 2-17 for major radionuclides. It is useful to take into account the fact that such conservatism is presented in the treatment of uncertainty in conformity assessment or in discussions on the stability of regulatory standards.
Related Concept Videos
Nuclear Stability
To hold positively charged protons together...
Clearance Models: Noncompartmental Models
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...
Radioactive Decay and Radiometric Dating
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Radioactivity and Nuclear Equations
A nuclide of an element has a specific number of protons and...
Nuclear Power
Nuclear Fuels
Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...

