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Feasibility of a Large Language Model Chatbot to Support Parental Understanding in the PICU
R Brandon Hunter1,2, Satid Thammasitboon1,2, Sreya Rahman1
1Department of Pediatrics, Baylor College of Medicine, Houston, TX.
Critical Care Explorations
|March 20, 2026
Summary
A large language model (LLM) chatbot effectively answered parental questions in the pediatric intensive care unit (PICU), showing high engagement and satisfaction. This supports its use in future randomized controlled trials (RCTs).
Area of Science:
- Artificial Intelligence in Medicine
- Clinical Informatics
- Patient Engagement Technologies
Background:
- Parental understanding of critical care is vital for family-centered care.
- Large language models (LLMs) offer potential for patient education and support.
- Existing communication tools in the Pediatric Intensive Care Unit (PICU) may not fully meet parental information needs.
Purpose of the Study:
- To assess the feasibility of an LLM-based chatbot for answering parental questions in the PICU.
- To gather data informing the design of a future randomized controlled trial (RCT).
Main Methods:
- A prospective, single-arm feasibility study involving 14 parents of children in a quaternary PICU.
- Parents interacted with a HIPAA-compliant GPT-4o chatbot for 10-minute sessions, using patient-specific electronic health record (EHR) data.
- Feasibility assessed via parental engagement, satisfaction, provider perceptions, accuracy, safety, and recruitment.
Main Results:
- High recruitment rate (87.5%) and parental engagement (median 6 questions).
- Excellent real-time satisfaction (96%) and perceived value (Net Promoter Score [NPS] +57).
- Chatbot responses were highly accurate (99.3%), with minor errors; providers rated quality highly (median 5.0/6.0).
Conclusions:
- An EHR-informed LLM chatbot is feasible for use in the PICU.
- The technology demonstrated high parental engagement, satisfaction, and provider acceptance.
- Findings support the progression to a larger randomized controlled trial (RCT).

