Related Experiment Video
Updated: Mar 22, 2026

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Continuous Measurement of Biological Noise in Escherichia Coli Using Time-lapse Microscopy
Published on: April 27, 2021
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Musing on noise and signal: Harnessing brakes to tame pervasive information
1Institut de Génétique Moléculaire de Montpellier, IGMM, Université Montpellier, CNRS, Montpellier, France.
Molecular Cell
|March 20, 2026
Abstract:
Extensive transcription of genetic information beyond annotated genes is an asset for cellular physiology and evolution, but it can blur functional messages and threaten genomic stability. In this issue of Molecular Cell, Polizzese et al. reveal how transcriptional brakes act specifically on non-coding sequences through nascent RNA recognition by the Restrictor.
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