Related Experiment Video
Updated: Mar 22, 2026

Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells
Published on: October 24, 2019
Oxidizing to optimize stemness and antitumor immunity
1Trev and Joyce Deeley Research Centre, BC Cancer, Victoria, BC, Canada; Basic and Translational Research, BC Cancer Research Institute, Victoria, BC, Canada; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada; The Metabolomics Consortium of BC, Victoria, BC, Canada; Institute of Health Literacy, Victoria, BC, Canada.
None:
In this issue of Cell Chemical Biology, Pang et al.1 address the question of how effector CD8⁺ T cells acquire stem-like durability. They uncover a redox-driven metabolic program in which NQO1-mediated cycling of lawsone enhances pentose phosphate pathway, remodels mitochondrial function, and connects effector differentiation to sustained antitumor immunity.
More Related Videos
05:08Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model
Published on: February 17, 2019
09:04Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
Related Concept Videos
Cancer Stem Cells and Tumor Maintenance
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer Stem Cells and Tumor Maintenance
Tumor Immunotherapy
Source And Potency Of Stem Cells
The Tumor Microenvironment
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell...