Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

Guidelines for Writing Outcome

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care evaluation by...

Methods of Documentation II: POMR

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.

Types of Reports I: Hand-off Report

Types of Reports I: Hand-off Report

A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:

Types of Reports III: Telephone and Verbal Reports

Types of Reports III: Telephone and Verbal Reports

Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Self-management of long COVID symptoms with over-the-counter medicines and other non-prescribed therapies: a cross-sectional survey.

BMC public health·2026

Same author

ZAP-X self-shielding gyroscopic radiosurgery: a scoping review of technical characteristics and early clinical experience.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026

Same author

From framework to practice: applying the proteus-practice framework to learn lessons for integrating PROs in clinical care.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026

Same author

Physiotherapist and nurse perspectives on the acceptability and timing of patient-reported outcome measures in clinical practice: Balancing standardisation and flexibility.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2026

Same author

Financial Hardship and Nonadherence to Lifestyle and Surveillance in Childhood Cancer Survivors.

JAMA network open·2026

Same author

Potential for risk reduction of chronic health conditions through lifestyle in childhood cancer survivors.

Nature communications·2026

Same journal

Are preference-weighted cancer-specific measures more sensitive than generic measures? A comparison of EQ-5D-5L, SF-6Dv2, FACT-8D and QLU-C10D in gastrointestinal cancers.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

Same journal

Development and Validation of a Brief Healthcare Insecurity Scale in a Sample of U.S. Adults Living with and without HIV.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

Same journal

A Competency Framework for Health Technology Assessment Expertise: Results from a Delphi Study.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

Same journal

Physician-led Switching from Reference Biologics to Biosimilars: What is the Effect on selected Health-Related Outcomes and Costs for IBD Patients in Germany?

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

Same journal

Critical Comments by the European Medicines Agency on Patient-Reported Outcomes in Regulatory Submissions (2020-2023).

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

Same journal

Interpreting the Economic Value of TPEx in Recurrent or Metastatic HNSCC: The Importance of Decision Context, Utility Timing, and Treatment Burden.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Designing and Implementing Real-World Patient-Reported Outcomes-Emerging Recommendations: A Good Practices Report of

Angela J Rylands¹, Konrad Maruszczyk², Olalekan Lee Aiyegbusi²

¹Kyowa Kirin International, London, England, UK.

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research

|March 20, 2026

Summary

This summary is machine-generated.

High-quality real-world patient-reported outcomes (RW-PROs) are crucial for decision-making. This report outlines nine methodological considerations for collecting robust RW-PRO data in routine care, balancing rigor with feasibility for patient-centered healthcare.

Keywords:

health technology assessment methodological guidance patient experience data patient-reported outcomes (PRO)prospective real-world studies real-world PROs (RW-PROs)real-world data (RWD)real-world evidence (RWE)regulatory decision making

More Related Videos

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

Related Experiment Videos

Last Updated: Jun 2, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Biomechanical Changes Related to Low Back Pain: An Innovative Tool for Movement Pattern Assessment and Treatment Evaluation in Rehabilitation

Published on: December 13, 2024

Area of Science:

Health Services Research
Clinical Informatics
Patient-Reported Outcomes

Background:

Real-world evidence (RWE) is increasingly used in regulatory, reimbursement, and clinical decisions.
Collecting high-quality patient-reported outcomes (PROs) outside traditional trials presents unique challenges.
Existing guidance inadequately addresses the methodological and operational complexities of prospective real-world PRO (RW-PRO) data collection.

Purpose of the Study:

To review methodological considerations for prospective PRO collection in real-world settings.
To examine how RW-PROs can complement clinical outcomes for capturing patient experience and treatment effectiveness.
To address stakeholder uncertainty regarding feasible and robust RW-PRO data generation for decision-making.

Main Methods:

A Task Force reviewed emerging methodological considerations for prospective RW-PRO collection.
Identified nine interrelated considerations for planning and implementing RW-PRO studies.
Examined the balance between scientific rigor, feasibility, patient burden, and operational constraints.

Main Results:

Nine key methodological considerations were identified: clear objectives, patient engagement, representativeness, instrument selection, data quality, feasible assessments, rigorous analysis, responsible technology use, and early engagement with regulatory bodies.
Best practices for RW-PRO research are context-dependent, varying by study, evidentiary use, and population.
The report outlines options, tradeoffs, strengths, and limitations rather than a single prescriptive model.

Conclusions:

RW-PRO evidence can inform regulatory and HTA decisions, enhance treatment outcome understanding, and support patient-centered care.
Transparent reporting of methodological choices and their implications is crucial for RW-PRO data interpretability.
Adopting emerging practices ensures RW-PRO data are meaningful, interpretable, and reflect patient-important outcomes.