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Published on: February 29, 2020
Prone Digital Subtraction Myelography versus Dynamic CT Myelography for Detecting Definite Type 1 CSF Leak in
Woo-Seok Ha1, Haram Joo1, Soomi Cho1
1From the Department of Neurology (W.-S.H., C.S., J.H., K.M.K., M.K.C.), Radiology (H.J., B.M.K., D.J.K.), Yonsei University College of Medicine, Seoul, Republic of Korea.
Background And Purpose:
Ventral dural tears (Type 1) are a major cause of spontaneous intracranial hypotension (SIH) and require precise localization for targeted treatment. Although prone digital subtraction myelography (DSM) and dynamic CT myelography (dCTM) are standard diagnostic modalities, their diagnostic performance has not been directly compared. We aimed to evaluate the diagnostic yield and radiation exposure of prone DSM compared with dCTM in a paired cohort.
Materials And Methods:
In this ambispective study, we analyzed 39 patients with Type 1 leaks who underwent both prone DSM and dCTM at a single tertiary center between July 2024 and September 2025. All images were independently re-evaluated by a blinded neurointerventionist using the SIH-RADS scoring system. The primary outcome was the rate of successful localization, defined as SIH-RADS Category 5. Secondary outcomes included the effective radiation dose and inter-rater reliability.
Results:
Successful localization was achieved in 31 patients (79.5%) using prone DSM and in 33 patients (84.6%) using dCTM, with no statistically significant difference between the two modalities (P = .72). Concordant localization was observed in 28 patients (71.8%). The median effective radiation dose of prone DSM was approximately half that of dCTM (P < .001). Diagnostic failures in DSM were primarily attributed to artifacts at the cervicothoracic junction, which were avoidable using the swimmer's position in the majority of the patients, whereas failures in dCTM were associated with temporal limitations or technical failures.
Conclusions:
Prone DSM and dCTM demonstrated comparably high diagnostic yields for localizing Type 1 leaks. However, DSM offered a significant advantage in radiation safety. When available and supported by appropriate expertise, prone DSM may be considered as a preferred first-line modality, with dCTM serving as a complementary option.
