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Updated: Mar 22, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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Feature reduction using swarm optimization and random forest classifiers for early diabetes risk prediction.

Proshenjit Sarker1, Abdullah-Al Nahid1, Kwonhue Choi2

  • 1Electronics and Communication Engineering Discipline, Khulna University, Khulna, 9208, Bangladesh.

Scientific Reports
|March 21, 2026
PubMed
Summary
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Diabetes Prediction Using Feature Selection Algorithms and Boosting-Based Machine Learning Classifiers.

Diagnostics (Basel, Switzerland)·2025

This study introduces advanced machine learning models for early diabetes detection, achieving high accuracy with significant feature reduction. Tuna Swarm Optimization with Random Forest (TSO_RF) demonstrated superior performance, identifying key risk factors like Polyuria and Polydipsia.

Area of Science:

  • Medical Informatics
  • Computational Biology
  • Artificial Intelligence in Healthcare

Background:

  • Diabetes mellitus is a chronic metabolic disorder with severe health implications, necessitating early detection.
  • Type 2 diabetes, characterized by insulin resistance or deficiency, poses a significant global health challenge.
  • Current early detection methods often involve numerous features, increasing patient burden and reducing efficiency.

Purpose of the Study:

  • To develop and evaluate machine learning models for efficient early diabetes risk prediction.
  • To achieve high accuracy while significantly reducing the number of predictive features.
  • To provide explainable AI insights into model behavior and feature importance.

Main Methods:

  • Three swarm-based metaheuristic algorithms (Fox Optimizer, Honey Badger Algorithm, Tuna Swarm Optimization) were integrated with a Random Forest Classifier.

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  • The Early Stage Diabetes Risk Prediction dataset, comprising 520 individuals and 16 predictors, was utilized.
  • Explainable AI techniques, specifically SHAP (SHapley Additive exPlanations), were employed for model interpretability.
  • Main Results:

    • Tuna Swarm Optimization with Random Forest (TSO_RF) achieved 100% accuracy without cross-validation and 98.14% mean 10-fold cross-validation accuracy.
    • TSO_RF utilized only 14 features, demonstrating effective feature reduction while maintaining high performance.
    • SHAP analysis identified Polyuria, Polydipsia, and Gender as critical predictors for diabetes risk.

    Conclusions:

    • The proposed TSO_RF model offers a highly accurate and efficient approach for early diabetes detection.
    • Significant feature reduction is achievable without compromising predictive performance.
    • Explainable AI provides crucial insights into the factors driving diabetes risk prediction.