Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Propagation of Action Potentials01:23

Propagation of Action Potentials

13.1K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
13.1K
Neural Circuits01:25

Neural Circuits

3.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.2K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

4.2K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DiabLLM: An LLM-Based Framework for Blood Glucose Prediction in Type 1 Diabetes.

IEEE journal of biomedical and health informatics·2026
Same author

Transforming [<sup>177</sup>Lu]Lu-PSMA-617 treatment planning: Machine learning-based radiodosiomics and swin UNETR using pretherapy PSMA positron emission tomography/computed tomography (PET/CT).

Medical physics·2025
Same author

Explainable artificial intelligence for pneumonia classification: Clinical insights into deformable prototypical part network in pediatric chest x-ray images.

Journal of medical imaging and radiation sciences·2025
Same author

Machine Learning-based Dose Prediction in [<sup>177</sup>Lu]Lu-PSMA-617 Therapy by Integrating Biomarkers and Radiomic Features from [<sup>68</sup>Ga]Ga-PSMA-11 Positron Emission Tomography/Computed Tomography.

International journal of radiation oncology, biology, physics·2025
Same author

Sync-GWO: Highly Private and Bandwidth-Efficient Federated Learning With a Case Study in Healthcare.

IEEE journal of biomedical and health informatics·2025
Same author

Automated segmentation of lesions and organs at risk on [<sup>68</sup>Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR.

Cancer imaging : the official publication of the International Cancer Imaging Society·2024
Same journal

A tri-axis optomechanical accelerometer with plasmonic MIM waveguide and structural direction-dependent optical signatures.

Scientific reports·2026
Same journal

Holographic leaky-wave antennas with independently controlled multiple counter-rotating vortex beams.

Scientific reports·2026
Same journal

Differential associations of longitudinal hearing and vision trajectories with dementia and mild cognitive impairment in older adults.

Scientific reports·2026
Same journal

Abdominal obesity and leisure-time sedentary behavior in relation to gastroesophageal reflux disease risk: a prospective cohort study from the UK Biobank.

Scientific reports·2026
Same journal

Effect of nitrogen-rich COF incorporation on the structure and separation performance of polyamide nanofiltration membranes.

Scientific reports·2026
Same journal

Withanolide A inhibits hIAPP aggregation: An In silico, biophysical, and drosophila-based In vivo validation.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions
07:34

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

Published on: March 25, 2014

10.3K

Backpropagation-free spiking neural networks with the forward-forward algorithm.

Mohammadnavid Ghader1, Saeed Reza Kheradpisheh2, Bahar Farahani3

  • 1Department of Computer and Data Science, Faculty of Mathematical Sciences, Shahid Beheshti University, Tehran, Iran.

Scientific Reports
|March 21, 2026
PubMed
Summary
This summary is machine-generated.

The Forward-Forward (FF) algorithm offers a more efficient and biologically plausible way to train Spiking Neural Networks (SNNs). This novel approach achieves competitive accuracy on complex tasks, overcoming limitations of traditional backpropagation.

More Related Videos

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.9K
Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.7K

Related Experiment Videos

Last Updated: Mar 22, 2026

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions
07:34

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

Published on: March 25, 2014

10.3K
Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

10.9K
Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.7K

Area of Science:

  • Computational Neuroscience
  • Artificial Intelligence
  • Machine Learning

Background:

  • Spiking Neural Networks (SNNs) mimic biological neurons using discrete spikes, offering potential efficiency.
  • Traditional backpropagation (BP) training for SNNs faces challenges in computational cost and biological realism.

Purpose of the Study:

  • To investigate the Forward-Forward (FF) algorithm as an alternative training method for SNNs.
  • To evaluate the performance of an FF-based SNN framework on various datasets.

Main Methods:

  • Implemented a novel FF-based training framework for SNNs.
  • Evaluated the framework on static (MNIST, Fashion-MNIST, Kuzushiji-MNIST) and spiking (Neuro-MNIST, SHD) datasets.
  • Compared performance against existing FF-based SNNs and backpropagation-trained SNNs.

Main Results:

  • The FF-based SNN model achieved superior performance over prior FF-SNNs on static datasets with a lighter architecture.
  • Accuracy comparable to state-of-the-art BP-trained SNNs was reached on static datasets.
  • Outperformed other SNN models on complex spiking tasks (SHD) and remained competitive with BP-SNNs.

Conclusions:

  • The FF algorithm presents a promising alternative for SNN training, enhancing efficiency and biological plausibility.
  • This approach addresses key limitations associated with backpropagation in SNNs.
  • FF-based SNNs show potential for advancing neuromorphic computing and AI applications.