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Updated: Mar 23, 2026

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Limited Access to Systemic Lupus Erythematosus: A Systematic Review
Pamela Munguía-Realpozo1,2, Claudia Mendoza-Pinto1,2, Ivet Etchegaray-Morales1
1Department of Rheumatology, Medicine School, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Current Rheumatology Reviews
|March 21, 2026
Summary
Systemic lupus erythematosus (SLE) care inequities impact marginalized groups. Addressing social determinants and using digital platforms can improve healthcare access and reduce disparities for SLE patients.
Area of Science:
- Rheumatology
- Health Services Research
- Health Equity
Background:
- Systemic lupus erythematosus (SLE) care disparities affect patient outcomes, interventions, and specific populations.
- Inequities exist across gender, race/ethnicity, and geographic regions.
- Understanding these disparities is crucial for improving SLE management.
Purpose of the Study:
- To systematically review literature on access to care for SLE patients.
- To identify key themes related to healthcare access barriers and facilitators.
- To explore potential solutions for addressing SLE care inequities.
Main Methods:
- Systematic literature review adhering to PRISMA guidelines.
- Searched major databases including PubMed, Scopus, Web of Science, Cochrane Library, and EBSCO.
- Included studies on economic burden, access barriers/facilitators, and solutions for SLE care.
Main Results:
- Identified 77 relevant articles.
- Revealed five critical issues: economic burden, access barriers/facilitators, utilization, adherence, and solutions.
- Social factors like transportation, insurance, and mental health access are significant barriers.
Conclusions:
- Healthcare access and utilization are influenced by socioeconomic status, ethnicity, education, and residency.
- Low education, SES, rural location, and depression impact adherence.
- Solutions include peer support, digital platforms (telemedicine), and community-based programs to reduce inequities.
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