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Interpreting patient-reported outcomes after ischemic stroke: defining minimal important difference in EQ-5D across

Pingping Li1, Min Zhao1, Yining Huang2

  • 1School of International Pharmaceutical Business, Economics & Arts Building, Jiangning Campus, China Pharmaceutical University, 639 Longmian Avenue, Jiangning District, Nanjing City, Jiangsu Province, 211198, China.

Health and Quality of Life Outcomes
|March 22, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
EQ-5DLongitudinal studyMinimal important differenceRecovery phaseStroke

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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.