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Updated: Mar 24, 2026

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
Published on: June 8, 2014
[Interdisciplinary consensus on the prevention of antiresorptive medication-related osteonecrosis of the jaw]
Zsolt Németh1, József Szalma2, Szilvia Mészáros3
11 Semmelweis Egyetem, Fogorvostudományi Kar, Arc-Állcsont-Szájsebészeti és Fogászati Klinika Budapest, Mária u. 52., 1085 Magyarország.
Abstract:
At the initiative of the Hungarian Association of Oral and Maxillofacial Surgeons, the Association of Hungarian Medical Societies organized an interdisciplinary forum entitled: "Interdisciplinary Consensus on the Prevention of Antiresorptive Medication-Related Osteonecrosis of the Jaw". The forum was held with the participation of the Hungarian Society for Osteology and Osteoarthrology, the Society of Hungarian Oncologists, the Hungarian Society of Clinical Oncology, the Hungarian Dental Association, the Hungarian Society for Dental Implantology, and the Online Organization of General Practitioners. The enclosed document was developed during the forum and the subsequent consultations, and reflects the standpoint of all participants. Given that the etiopathogenesis of the condition is not fully understood and that no effective therapeutic option is currently available, prevention is of paramount importance. The above-mentioned societies and the patients under their care share a common interest in minimizing the adverse effects of antiresorptive drugs which - when correctly indicated - are undeniably effective. Another goal is to dispel the fear and defensive attitudes originating from the lack of information (sometimes observed in both patients and physicians), which may lead to delay in necessary treatments or omission of antiresorptive therapy. Some of the disciplines listed above are those in which these adverse effects may arise during routine clinical care, while others are involved in the management of established osteonecrosis. Owing to its preventive focus and professional scope, the consensus document is well suited to provide guidance for physicians prescribing antiresorptive therapy and for dentists, regarding appropriate patient management, the timing of interventions, and interdisciplinary collaboration. Orv Hetil. 2026; 167(12): 450-455.
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