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Published on: October 29, 2014
Outcomes in Children With Enterovirus Meningitis in London, England: A Retrospective Multicenter Cohort Study,
Jonathan Broad1, Luca Zombori2, Blanca Bravo Queipo-de-Llano3,4
1Department of Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
None:
Nonpolio enteroviruses are the most common cause of meningitis in children. We conducted a retrospective case series of long-term outcomes in 243 children between 1 January 2013 and 31 December 2023 across 4 tertiary centers in London. Adverse outcomes were associated with the absence of fever at presentation (odds ratio [OR], 4.65; 95% CI, 1.03-20.83), the presence of seizures (OR, 7.40; 95% CI, 1.05-51.96), and the presence of comorbidities at baseline (OR, 5.27; 95% CI, 1.18-23.47). Full recovery was seen in 153 of 160 (95.6%) children who were <3 months of age. These data may help clinicians to counsel parents and policy makers on streamlining care pathways following hospital discharge.
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