Related Experiment Video
Updated: Mar 24, 2026
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Thoracoscopic segmentectomy versus lobectomy for early-stage non-small cell lung cancer: efficacy, postoperative
Dejun Shu1, Jiyang Tang1, Weifu Zhou1
1Department of Thoracic Surgery, The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University) Zunyi 563000, Guizhou, China.
Objective:
To compare the clinical outcomes of thoracoscopic segmentectomy (TSE) and lobectomy (TLE) in early-stage non-small cell lung cancer (NSCLC) patients.
Methods:
A total of 129 patients with early-stage NSCLC (ES-NSCLC) treated at the First People's Hospital of Zunyi between May 2022 and May 2024 were retrospectively enrolled. Patients were divided into a control group (n=62; undergoing TLE) and a research group (n=67; undergoing TSE) based on their surgical approach. Surgical outcomes, intraoperative hemorrhagic blood loss, number of lymph nodes resected, surgical duration, chest drain duration and volume, minute ventilation, length of hospital stay, Visual Analogue Scale (VAS) scores, pulmonary function (PF), arterial blood gas parameters, postoperative complications, and prognosis was compared between the two groups.
Results:
Resection efficacy, lymph node harvest, chest tube duration, overall morbidity rate, and 1-year survival/recurrence were comparable between the two groups. However, TSE was associated with reduced intraoperative bleeding, shorter procedure time, lower postoperative drainage volume, shorter hospitalization time, and lower pain scores on postoperative days 1 and 5, with better minute ventilation values. Although PF and partial pressure of oxygen (PaO2) in the research group decreased on postoperative day 5 compared with baseline, they remained markedly higher than the control group. Additionally, the arterial carbon dioxide partial pressure (PaCO2) of the research group, though comparable to the preoperative level, was notably reduced compared to controls.
Conclusion:
TSE for ES-NSCLC is associated with improved ventilation volume, shorter hospital stays, alleviated postoperative pain, and better preservation of PF and arterial blood gas parameters.
