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Influenza A-Associated Acute Necrotizing Encephalitis With Complete Recovery Following Early Immunomodulatory Therapy
Adeola A Adeleke1, Sarah M Wall2, Shannon L Andrews2
1Primary Care, Touro College of Osteopathic Medicine, Middletown, USA.
A child with influenza A (H1N1) developed acute necrotizing encephalitis (ANE). Prompt immunomodulatory therapy led to complete neurological recovery, highlighting early diagnosis and targeted treatment importance.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Neuroimmunology
Background:
- Acute necrotizing encephalitis (ANE) is a severe neurological complication often following viral infections.
- Influenza A (H1N1) infection can trigger rapid neurological deterioration in young children.
- Elevated cytokines in cerebrospinal fluid (CSF) suggest central nervous system (CNS) immune activation in ANE.
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