Related Experiment Video
Updated: Mar 24, 2026

08:24
Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans
Published on: February 27, 2018
14.5K
Immunocompetent but Not Immune: A Prolonged Course of Cryptococcal Meningitis
Carlos Fagundo1, Abdul Rahman Omari1, Mauricio Valenzuela1
1Internal Medicine, BayCare Medical Group, Tampa, USA.
Cureus
|March 23, 2026
Summary
Cryptococcal meningitis (CM) can occur in immunocompetent individuals, presenting unique challenges. This case shows prolonged positive cultures despite treatment, emphasizing aggressive management for better outcomes.
Area of Science:
- Infectious Diseases
- Neuroscience
- Medical Mycology
Background:
- Cryptococcus neoformans typically infects immunocompromised individuals, causing cryptococcal meningitis (CM).
- CM in immunocompetent hosts is rare, often presenting atypically.
- Persistent positive cerebrospinal fluid (CSF) cultures challenge standard antifungal therapy.
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