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Primary vaginal yolk sac tumor in an 11-month-old girl: a case report
1Department of Radiology, Wuhan Children's Hospital Graduate Joint Training Base, School of Medicine, Wuhan University of Science and Technology, Wuhan, China.
Insights
Extragonadal yolk sac tumors are rare. This case highlights successful surgical resection and chemotherapy (bleomycin, etoposide, cisplatin) for a vaginal yolk sac tumor in an infant, offering a potential treatment approach.
Area of Science:
- Pediatric Oncology
- Gynecologic Pathology
Background:
- Extragonadal yolk sac tumors are exceptionally rare.
- Vaginal yolk sac tumors present diagnostic challenges in infants, often mimicking other conditions like hematomas.
- This case underscores the importance of considering rare tumors in the differential diagnosis of unexplained vaginal masses in infants.
Background:
Extragonadal yolk sac tumors are exceedingly rare. This report describes a vaginal yolk sac tumor in an infant to highlight key diagnostic and therapeutic aspects and its inclusion in the differential diagnoses of unexplained vaginal masses.
Case Presentation:
An 11-month-old girl presented with intermittent vaginal bleeding, initially misdiagnosed as a hematoma. Pathological examination confirmed yolk sac tumors. She underwent hysteroscopic resection and six cycles of PEB (bleomycin, etoposide, cisplatin) chemotherapy. No recurrence occurred during the 12-month follow-up.
Conclusion:
Primary vaginal yolk sac tumors are extremely rare and lack standardized treatment. Surgery combined with PEB chemotherapy proved effective in this case.
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