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Updated: Mar 24, 2026

Replication of the Ordered, Nonredundant Library of Pseudomonas aeruginosa strain PA14 Transposon Insertion Mutants
Published on: May 4, 2018
Pseudomonas aeruginosa strains lack tissue specificity
1Departments of Microbiology-Immunology and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
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Bacterial pathogens vary markedly from species to species in their capacity to cause different types of infection. A recent study by Penaranda and colleagues in mSystems shows that the genetic backgrounds of Pseudomonas aeruginosa isolates do not dictate whether they infect the lungs, blood, urine, or other body sites (C. Penaranda, E. P. Brenner, A. E. Clatworthy, L. A. Cosimi, et al., mSystems 11:e01362-25, 2026, https://doi.org/10.1128/msystems.01362-25). These findings suggest that each P. aeruginosa strain is versatile and has the potential to infect a variety of tissues and organs.
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