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Using Optical Coherence Tomography in Pediatric Neuro-ophthalmology
Hannah Rose Hashimi Tea1, Keely Roberson, Mays El-Dairi
1Department of Ophthalmology, Duke University Medical Center, Durham, NC.
International Ophthalmology Clinics
|March 23, 2026
Summary
Optical coherence tomography (OCT) offers valuable insights in pediatric neuro-ophthalmology. This guide details practical methods for obtaining and interpreting reliable OCT images in children, facilitating routine clinical use.
Area of Science:
- Pediatric Neuro-ophthalmology
- Ophthalmology Imaging
- Medical Technology Integration
Background:
- Optical coherence tomography (OCT) is established in adult neuro-ophthalmology but underutilized in pediatrics.
- Perceived barriers include technical, financial, and practical challenges to pediatric OCT adoption.
Purpose of the Study:
- To provide a pragmatic framework for integrating OCT into pediatric neuro-ophthalmology clinics.
- To guide clinicians in obtaining reliable OCT images in awake children and interpreting findings.
Main Methods:
- Review of technical aspects of tabletop and handheld OCT in children (positioning, fixation).
- Outline of key clinical OCT modalities (single-line scans, cube maps) and interpretation strategies.
- Structured approach combining RNFL and GCL measurements for differential diagnosis.
Main Results:
- Demonstrates OCT's utility in diagnosing conditions like papilledema, optic neuritis, and optic atrophy in children.
- Highlights strategies for accurate interpretation, including correcting for axial length and identifying segmentation errors.
- Shows how OCT can narrow differential diagnoses and guide urgent workups for decreased vision.
Conclusions:
- OCT can be a routine, child-friendly extension of the pediatric neuro-ophthalmic examination.
- Practical guidance facilitates overcoming barriers to pediatric OCT implementation.
- OCT enhances diagnostic capabilities for various pediatric optic nerve and retinal conditions.
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