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Complete genomes of Escherichia coli isolates encoding the EatA autotransporter from pediatric sources

Bernadette A Hritzo1,2,3, Jane M Michalski Wilhelm1,2,3, David A Rasko1,2,3,4

  • 1Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Microbiology Resource Announcements
|March 23, 2026
PubMed

Keywords:
ETECEatAEscherichia coligenomeplasmidvirulence

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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