Related Experiment Video
Updated: Mar 25, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Evidence-Based Nutritional Management of Menopausal Symptoms: A Pathophysiological Reasoning Approach to Personalized
Eleanor Reid1, Michelle Barrow1, Bea Cutler1
1The Centre for Nutritional Education and Lifestyle Management (CNELM), Wokingham, UK.
Personalized nutrition improved energy and sleep in a menopausal woman by addressing blood sugar imbalance and HPA axis function. This case report highlights the potential of tailored dietary interventions for women's health.
Area of Science:
- Nutritional Science
- Endocrinology
- Women's Health
Background:
- A 47-year-old woman experienced fatigue, mood instability, and bloating, seeking support for energy and bone health.
- Hormone replacement therapy (HRT) did not fully resolve symptoms, prompting further investigation.
- Family history of osteoporosis (OP) indicated a need for bone health support.
Purpose of the Study:
- To present the methodology and outcomes of a personalized nutrition intervention for a menopausal woman.
- To detail the pathophysiological reasoning used for patient assessment and intervention.
- To evaluate the efficacy of tailored dietary and lifestyle changes.
Main Methods:
- A 7-week intervention with two online consultations.
- Dietary analysis revealed macronutrient intake contributing to blood sugar imbalance and HPA axis dysfunction.
- Interventions included adjusted macronutrient intake, supplementation, weight-bearing exercise, caffeine reduction, yoga, and meditation.
Main Results:
- The patient reported increased energy, reduced snacking, and improved sleep.
- Mood and bloating remained unchanged; headaches worsened.
- Bone health was not quantitatively measured during the intervention.
Conclusions:
- Personalized nutrition, guided by pathophysiological reasoning, shows potential efficacy in improving energy and sleep.
- An evidence-based approach supports intervention decisions in nutritional coaching.
- Further research is needed to confirm bone health outcomes and address persistent symptoms.
More Related Videos
Related Concept Videos
Menopause
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Atherosclerosis III: Management
Cancer Prevention
Some...
Irritable Bowel Syndrome III: Medical and Nursing Management

