Related Experiment Video
Updated: Mar 25, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Chemical insights into marine lipid oxidation and its dual role in atherosclerosis: implications for food processing
Jing Xue1, Ziyang Hu2, Hongjie Chen2
1Zhejiang Key Laboratory of Food Microbiology and Nutritional Health, Collaborative Innovation Center of Seafood Deep Processing, Institute of Seafood, Zhejiang Gongshang University, Hangzhou 310012, China; Panvascular Diseases Research Center, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou 324000, China.
Abstract:
This review systematically summarizes recent advances concerning the contribution of marine-derived functional lipids and their oxidation-derived metabolites to atherosclerosis. It specifically focuses on the dual role of marine lipid oxidation: the oxidative processes generate a metabolite spectrum ranging from harmful compounds to beneficial specialized pro-resolving mediators (SPMs), which critically determines their ultimate health efficacy. From a chemical perspective, this review delves into how such duality modulates core mechanisms of atherosclerosis, including inflammation, oxidative stress, and cellular homeostasis. This chemical insight provides direct guidance for food technology, underscoring that optimizing extraction and stabilization processes is essential for preserving beneficial lipid profiles. Translating these insights into effective functional foods requires future research to concentrate on oxidation mechanisms, synergistic regulation, and population-based functional food development. By integrating marine lipid chemistry, food processing, and cardiovascular health, this review establishes a systematic framework for the science-based development of functional foods.
More Related Videos
Related Concept Videos
Atherosclerosis III: Management
Radical Autoxidation
Lipid-derived Compounds in the Human Body
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Atherosclerosis I: Introduction
Lipids: Dietary Sources and Requirements
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

