Clinical and economic burden of preseptal cellulitis in children: a 6-year review

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Çağla Özbakır1, Deniz Ergün2, Pelin Kaçar2

  • 1Department of Pediatrics, University of Health Sciences Dr. Behçet Uz Children's Hospital, İzmir, Türkiye.

The Turkish Journal of Pediatrics
|March 23, 2026
PubMed

Insights

Hospitalized children with preseptal cellulitis incur significant costs, primarily driven by length of stay. Understanding clinical factors is key to managing the economic burden of this common pediatric infection.

Area of Science:

  • Pediatric infectious diseases
  • Health economics
  • Ophthalmology

Background:

  • Preseptal cellulitis in children often leads to hospitalization, presenting clinical and economic challenges.
  • Current data on pediatric preseptal cellulitis clinical characteristics and cost distribution are limited.
  • Hospitalization involves intravenous antibiotics, imaging, lab tests, and consultations, increasing healthcare costs.

Purpose of the Study:

  • To evaluate the clinical and economic burden of preseptal cellulitis in hospitalized children.
  • To identify clinical factors associated with healthcare costs in pediatric preseptal cellulitis.

Main Methods:

  • Retrospective study of 166 children (1 month to 18 years) hospitalized with preseptal cellulitis (Jan 2019-Dec 2024).
  • Patients categorized by age and predisposing factors.
  • Analysis of length of stay, total hospital costs, and cost components based on clinical characteristics.

Main Results:

  • Most common symptoms included periorbital swelling (96.4%) and erythema (75.3%).
  • Median length of stay was 5 days, with no significant differences across age, sex, or predisposing factors.
  • A strong positive correlation (rho=0.775) was observed between length of stay and total hospital cost.

Conclusions:

  • Length of stay is a significant predictor of total healthcare costs in pediatric preseptal cellulitis.
  • Further research into cost-effective management strategies for pediatric preseptal cellulitis is warranted.
Abstract

Keywords:
antibiotichospital costsinusitis

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