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Risk Factors and Interventional Predictors for Postoperative Malunion and Nonunion in Adult Mandibular Fractures: A
Pranav S Tadepalli1, Julian Scaccia1, Shaan R Patel2
1Medical College, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Cureus
|March 24, 2026
Summary
Timely open reduction and internal fixation (ORIF) surgery for mandibular fractures reduces malunion and nonunion risks. Delayed intervention, smoking, alcohol use, and poor patient education increase complication rates.
Area of Science:
- Oral and Maxillofacial Surgery
- Trauma Surgery
- Orthopedic Surgery
Background:
- Mandibular fractures are common oral and maxillofacial surgery injuries.
- Malunion and nonunion are significant, underreported complications of facial fracture healing.
- Malocclusion is a well-studied complication, but malunion/nonunion require further investigation.
Purpose of the Study:
- To evaluate risk factors, predictors, surgical variables, and management strategies for postoperative malunion or nonunion in mandibular fractures.
- To synthesize current evidence on complications following mandibular fracture repair.
- To identify key factors influencing healing outcomes in mandibular fractures.
Main Methods:
- Scoping review of PubMed, Embase, Web of Science, and Google Scholar (2000-2025).
- Inclusion of prospective and retrospective clinical studies on mandibular fracture management.
- Exclusion of systematic reviews, meta-analyses, case reports, pediatric, and non-English studies.
Main Results:
- Open reduction and internal fixation (ORIF) showed lower malunion/nonunion rates than closed reduction, especially for comminuted fractures.
- Delayed surgical intervention (6-7 days post-injury) increased malunion/nonunion rates.
- Risk factors include posterior fractures, comminution, smoking, alcohol abuse, poor patient education, and advanced age.
Conclusions:
- Timely ORIF with stable fixation is associated with reduced malunion/nonunion rates in mandibular fracture repair.
- Delayed intervention and inadequate patient education are significant risk factors for complications.
- Consideration of these factors is crucial for minimizing postoperative complications.
Keywords:
complicationmalunionmandibular fracturemaxillo facial traumamaxillo-facial traumamaxillomandibular fixationnonunionopen reduction internal fixationrisk factortrauma
