Use of VISIA-CR Generation 5 in Aesthetic Skin Assessment: A Single-Case Review

Traditional evaluations of nonsurgical aesthetic treatments often rely on clinical photography and patient-reported outcomes, which are subjective and may overlook subtle or subsurface changes. Advanced imaging technologies, such as the VISIA-CR system, have increased objectivity; however, earlier generations provided limited parameters and lacked integrated analytics. The aim of this review was to illustrate the enhanced capabilities of the VISIA-CR Generation 5 system (VISIA-CR 5) and explore its clinical relevance through a single-case example. A 49-year-old female with Fitzpatrick skin phototype III underwent a combined treatment with intense pulsed light, a fractionated 1927 nm laser, and a dual-wavelength 1470/2940 nm laser. Standardized VISIA-CR 5 imaging was performed at baseline and 3 months. The system captured multispectral images and quantified 8 skin features (visible spots, brown spots, red spots, ultraviolet (UV) spots, texture, pores, porphyrins, and wrinkles) using expanded multiparameter analytics. The VISIA-CR 5 provided multidimensional assessment beyond conventional visual evaluation by quantifying feature intensity, background skin tone, and relative contrast. Although the mean intensity of visible, brown, and UV spots appeared darker at 3 months, contrast-based analysis indicated improved skin tone uniformity. The system also detected reduced fractional area alongside increased count for visible and UV spots, suggesting fragmentation of larger spots rather than proliferation, a level of detail unattainable with traditional methods. This case demonstrates that the VISIA-CR 5 can provide detailed imaging and integrated analytics that support comprehensive, objective evaluation of aesthetic treatment outcomes. Its expanded parameters facilitate detection of subtle, clinically relevant changes and highlight its potential utility in clinical research and practice. Level of Evidence: 4 (Therapeutic).