Related Experiment Video
Updated: Mar 25, 2026
07:32
Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
Published on: April 12, 2024
2.1K
Paraneoplastic Hepatitis Associated with Relapsed Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Jasmin Nelissen1, Sandra Coenen2, King Lam3
1Department of Hematology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.
Hematology Reports
|March 24, 2026
Summary
Paraneoplastic hepatitis, a rare liver complication, can present indolently in patients with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL). This case highlights a fibrosing form requiring early recognition and tailored immunosuppressive management.
Area of Science:
- Hepatology
- Oncology
- Immunology
Background:
- Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is an indolent B-cell lymphoma known for late relapses.
- Hepatic manifestations in lymphoproliferative disorders are known, but paraneoplastic hepatitis is rare and typically acute.
- This case presents an unusual indolent and progressive paraneoplastic hepatitis in a patient with relapsed NLPHL.
Related Concept Videos
01:15Secondary Lymphoid Organs
10.2K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
10.2K
01:25Hepatitis
34
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
34