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Updated: Mar 27, 2026

Determining the Contribution of the Energy Systems During Exercise

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Published on: March 20, 2012

Relation between Exercise Training-Induced Changes in Oxygen Uptake Kinetics and the Power-Duration Relation.

Tze-Huan Lei¹, Luuk Vos², I-Lin Wang¹

¹College of Physical Education, Hubei Normal University, Huangshi, CHINA.

Medicine and Science in Sports and Exercise

|March 24, 2026

Summary

Exercise training improves critical power (CP) and oxygen uptake kinetics (τVO2) by enhancing oxidative phosphorylation. Changes in work capacity (W’) and the slow component of oxygen uptake (V̇O2sc) are more complex, involving multiple bioenergetic factors.

Keywords:

COMPUTER MODEL CRITICAL POWER EXERCISE BIOENERGETICS OXYGEN UPTAKE KINETICS POWER-DURATION RELATION

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Published on: February 20, 2018

Area of Science:

Exercise Physiology
Skeletal Muscle Bioenergetics
Human Performance

Background:

The power-duration relationship (CP and W') and pulmonary oxygen uptake (V̇O2) kinetics (τVO2 and V̇O2sc) are key determinants of endurance exercise capacity.
Understanding the interplay between these physiological variables and their adaptation to training is crucial for optimizing exercise prescriptions.

Purpose of the Study:

To investigate the relationships between training-induced changes in critical power (CP), work capacity (W'), and pulmonary oxygen uptake (V̇O2) kinetics (τVO2 and V̇O2sc).
To elucidate the underlying bioenergetic mechanisms responsible for these training adaptations using computational modeling.

Main Methods:

Eleven healthy untrained males completed 2 weeks of severe-intensity exercise training.
Physiological assessments included V̇O2max, CP, W', and V̇O2 kinetics before and after training.
A validated computer model of skeletal muscle bioenergetics was employed to analyze training-induced changes.

Main Results:

Critical power (CP) and the time constant of pulmonary oxygen uptake (τVO2) were strongly inversely correlated, with training-induced changes also correlating.
Computer simulations indicated increased oxidative phosphorylation (kOX) as the primary driver for improvements in CP and τVO2.
Work capacity (W') increased, and the slow component of oxygen uptake (V̇O2sc) amplitude decreased post-training, but these changes were not directly correlated, suggesting complex bioenergetic regulation.

Conclusions:

The bioenergetic mechanisms underlying critical power (CP) and oxygen uptake kinetics (τVO2) appear to be closely linked.
The adaptations in work capacity (W') and the slow component of oxygen uptake (V̇O2sc) are influenced by a more complex interplay of bioenergetic factors, including accessible phosphate pools and peak inorganic phosphate concentrations.