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Acute renal failure after dietary change - a case report
Eric Jankowski1, J Reindl2, L Hauptmann2
1Department of Internal Medicine III, University Hospital Jena, Friedrich Schiller University, Am Klinikum 1, 07747, Jena, Germany. Eric.jankowski@med.uni-jena.de.
BMC Nephrology
|March 25, 2026
Summary
A vegetarian diet change led to acute kidney failure in a woman due to oxalate nephropathy from Swiss chard. Dietary intervention improved kidney function, highlighting the importance of nutritional management for oxalate nephropathy.
Area of Science:
- Nephrology
- Dietary Medicine
- Toxicology
Background:
- Oxalate nephropathy (ON) is a rare but severe kidney disease caused by calcium oxalate crystal deposition.
- It leads to chronic kidney disease with a poor prognosis and limited treatment options.
Purpose of the Study:
- To report a case of acute kidney failure secondary to oxalate nephropathy.
- To emphasize the role of dietary modifications in managing oxalate nephropathy.
Main Methods:
- A case study of a 59-year-old female with acute renal failure after consuming Swiss chard.
- Kidney biopsy confirmed acute tubular damage and oxalate crystal deposition.
- Treatment involved conservative management and a low-oxalate diet.
Main Results:
- Kidney function and size improved within 4 weeks of dietary intervention.
- Baseline estimated glomerular filtration rate (eGFR) was restored after one year on a low-oxalate diet.
- No evidence of chronic kidney damage was found.
Conclusions:
- Dietary patterns significantly impact acute kidney injury.
- Further research is needed on the oxalate crystal deposition threshold for clinically significant oxalate nephropathy.
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