Related Experiment Video
Updated: Mar 27, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Intractable Elevated Intraocular Pressure during Plaque Brachytherapy for Posterior Choroidal Tumors: A Case Report
Mohamed Belmouhand1, Jens Folke Kiilgaard1,2, Carsten Faber1,2
1Department of Ophthalmology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Introduction:
Uncontrolled elevated intraocular pressure (IOP) during brachytherapy for posterior choroidal tumors is unreported. We present 2 patients who both experienced intractable elevated IOP during plaque brachytherapy.
Case Presentation:
Both patients experienced persistent elevated IOP unresponsive to all pressure-lowering agents following surgery that included transvitreal retinochoroidal biopsy and ruthenium-106 plaque application for posterior choroidal tumors in the superior quadrants. During plaque placement in patient 1, a large, dilated vortex vein was observed in the area where the plaque was to be placed. After plaque removal in both patients, IOP normalized without the need for additional pressure-lowering therapy.
Conclusion:
We hypothesize that the clinical presentation in both patients was primarily attributable to two factors: first, pre-existing venous congestion and, second, the application of a plaque, which obstructed a superior vortex vein. This left the remaining vortex veins unable to compensate for the obstruction, leading to intractable IOP during plaque brachytherapy.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Glaucoma: Overview
Ophthalmic Drug Delivery Systems

