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Ultra-Sensitive Wireless Capacitive Nanocomposite-Based Pressure Sensors for Health Monitoring.

Seyedamin Hashemi1, Saman Ebrahimibasabi2, Mostafa Sajjadi3

  • 1School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287, USA.

Advanced Materials Technologies
|March 25, 2026
PubMed
Summary

This study introduces a novel wireless pressure sensor using a zinc oxide (ZnO) nanocomposite dielectric layer, significantly boosting sensitivity for medical applications like intracranial pressure (ICP) monitoring.

Keywords:
LC resonatorsZnO nanoparticlesintracranial pressure monitoringnanocomposite dielectric layersultra-sensitive pressure sensorswireless pressure sensing

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Wireless pressure sensors are vital for healthcare applications, including monitoring physiological pressures like intracranial pressure (ICP).
  • Enhancing the sensitivity and in vivo performance of these sensors is a critical challenge for clinical translation.
  • Current wireless capacitive pressure sensors require improvements in sensitivity and operational range.

Purpose of the Study:

  • To develop a novel wireless capacitive pressure sensor with enhanced sensitivity and extended reading distance.
  • To investigate the use of a biocompatible zinc oxide (ZnO) and styrene-ethylene-butylene-styrene (SEBS) nanocomposite dielectric layer.
  • To demonstrate the in vivo efficacy of the developed sensor for physiological pressure monitoring.

Main Methods:

  • Fabrication of a pyramid-structured dielectric layer by incorporating ZnO nanoparticles into SEBS at varying concentrations.
  • Characterization of sensor performance, including sensitivity and operational pressure range.
  • Development of a novel pickup probe to enhance wireless reading distance.
  • In vivo testing of the sensor for detecting intracranial pressure (ICP) changes in murine models.

Main Results:

  • Sensors utilizing a 0.7% ZnO (v/v) nanocomposite dielectric layer showed a 4.3-fold increase in sensitivity compared to pure SEBS.
  • Achieved a high sensitivity of 45 MHz mmHg⁻¹ within a pressure range up to 25 mmHg.
  • The new pickup probe extended the wireless reading distance by 40% compared to conventional probes.
  • Successfully demonstrated reliable in vivo detection of ICP variations in murine models.

Conclusions:

  • The developed wireless capacitive pressure sensor with a ZnO/SEBS nanocomposite dielectric layer offers significantly enhanced sensitivity and stability.
  • The improved sensor design and novel pickup probe show great clinical potential for non-invasive physiological pressure monitoring.
  • This technology enables wireless sensing without complex electronics, paving the way for advanced medical devices.