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Updated: Mar 27, 2026

Studying Microbial Communities In Vivo: A Model of Host-mediated Interaction Between Candida Albicans and Pseudomonas Aeruginosa in the Airways
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Effect of transient versus persistent Aspergillus colonisation on clinical outcomes in bronchiectasis

Allison Michaud1, Julie Jarand1, Christina S Thornton1,2

  • 1Division of Respirology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

ERJ Open Research
|March 25, 2026
PubMed

Insights

Persistent Aspergillus infection in bronchiectasis patients leads to more frequent exacerbations and faster lung function decline. This finding highlights the impact of Aspergillus colonization on respiratory health.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Microbiology

Background:

  • Bronchiectasis is a chronic lung condition characterized by airway damage and mucus buildup.
  • Recurrent respiratory infections are common in bronchiectasis, leading to disease progression.
  • Aspergillus fumigatus is a common fungus found in the environment, and its colonization can occur in the airways of patients with chronic lung diseases.

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