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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

441
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
441
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

556
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
556

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Updated: Mar 27, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
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Transcatheter Paravalvular Leak Closure Using Valve Frame Access.

Chloe Kharsa1, Mangesh Kritya1, Karl Abou Zeid1

  • 1Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.

JACC. Case Reports
|March 25, 2026
PubMed
Summary
This summary is machine-generated.

Transcatheter paravalvular leak (PVL) closure after transcatheter aortic valve replacement (TAVR) can be effectively managed using frame-based access. Careful computed tomography planning identifies optimal access for device delivery, reducing PVL in select patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Transcatheter aortic valve replacement (TAVR) is a common procedure for aortic stenosis.
Keywords:
Evolut FX+multimodality imagingparavalvular leakpercutaneous closuretranscatheter aortic valve replacement

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  • Paravalvular leak (PVL) is a potential complication following TAVR, leading to adverse outcomes.
  • Current PVL management strategies may be limited by patient anatomy and device characteristics.