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Correction: Patients with Langerhans cell histiocytosis and hypothalamic-pituitary involvement: insights from the

Hiba Masri Iraqi1,2,3, Marina Tsoli4, Mattia Barbot5,6

  • 1Rabin Medical Center, Petah Tiqva, Israel. iraqihiba@yahoo.com.

Pituitary
|March 25, 2026
PubMed
Abstract

No abstract available in PubMed .

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Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...

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