Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impaired visually guided behavior in a mouse model of Parkinson's disease.

Journal of neurophysiology·2025

Same author

Paradoxical Boosting of Weak and Strong Spatial Memories by Hippocampal Dopamine Uncaging.

eNeuro·2024

Same author

Activity-dependent organization of prefrontal hub-networks for associative learning and signal transformation.

Nature communications·2023

Same author

Reversal of pathological motor behavior in a model of Parkinson's disease by striatal dopamine uncaging.

PloS one·2023

Same author

Editorial: Reconfiguration of neuronal ensembles throughout learning.

Frontiers in systems neuroscience·2023

Same author

Conceptual framework for neuronal ensemble identification and manipulation related to behavior using calcium imaging.

Neurophotonics·2022

Same journal

Protocol for ultrasound-guided injection into the murine portal vein to initiate liver metastasis.

STAR protocols·2026

Same journal

Protocol for semi-automatic quantitative bioimaging analysis of synapse loss.

STAR protocols·2026

Same journal

Protocol for integrated ubiquitination analysis of in vitro E3 ligase-DUB regulation and in vivo ubiquitin chain linkage characterization.

STAR protocols·2026

Same journal

Protocol for constructing multi-ancestry polygenic models using S4-Multi.

STAR protocols·2026

Same journal

Protocol for inducing deep vein thrombosis in C57BL/6J mice using the inferior vena cava stenosis model.

STAR protocols·2026

Same journal

Overcoming the challenges of genome-editing essential genes.

STAR protocols·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 27, 2026

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

Protocol for identifying and comparing neuronal ensembles using different algorithms within a graphical user

Ricardo Velazquez-Contreras¹, Luis Carrillo-Reid¹

¹Neurobiology Institute, UNAM, Juriquilla, Querétaro 76230, México.

|March 25, 2026

Summary

This summary is machine-generated.

This study introduces ENCORE, a software tool for identifying and comparing neuronal ensembles from brain activity data. ENCORE facilitates the analysis of neural circuits and their functions.

Keywords:

Behavior Computer sciences Neuroscience

More Related Videos

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

Published on: February 10, 2017

Related Experiment Videos

Last Updated: Mar 27, 2026

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms

Published on: March 3, 2023

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'

Published on: February 10, 2017

Area of Science:

Neuroscience
Computational Neuroscience
Systems Neuroscience

Background:

Neuronal ensembles, defined by coordinated neural activity, are fundamental to specific brain functions.
Analyzing these ensembles requires sophisticated methods to process complex neural data.
Existing tools may lack a unified approach for identification and comparison.

Purpose of the Study:

To present a novel protocol and software tool, ENCORE, for the identification and comparison of neuronal ensembles.
To provide a user-friendly graphical interface for analyzing neural activity data from various sources.
To enable robust evaluation of the functional relevance of identified neuronal ensembles.

Main Methods:

Development of a unified graphical user interface (ENCORE) for neuronal ensemble analysis.
Protocol includes installation, data loading, ensemble identification, and results inspection.
Comparison of five distinct algorithms for neuronal ensemble identification is detailed.
Procedures for assessing the functional relevance of identified ensembles are outlined.

Main Results:

ENCORE provides a standardized protocol for identifying and comparing neuronal ensembles.
The software integrates data from two-photon microscopy and electrophysiological recordings.
Comparative analysis of algorithms aids in selecting optimal methods for specific research questions.
The protocol facilitates the evaluation of functional significance of neural populations.

Conclusions:

ENCORE offers a comprehensive solution for the analysis of neuronal ensembles.
The tool enhances the ability to study neural circuits and their functional roles.
This protocol standardizes and simplifies the complex process of neural ensemble analysis.