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Related Experiment Video

Updated: Mar 27, 2026

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Expert Practical Recommendations for Hepatocellular Carcinoma.

Feng Su1,2, Alejandro Torres-Hernandez2,3, Ryan Hickey4

  • 1Division of Gastroenterology and Hepatology, Department of Medicine, NYU Grossman School of Medicine, New York, New York, United States.

Seminars in Liver Disease
|March 25, 2026
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Summary

Hepatocellular carcinoma (HCC) management has advanced with immunotherapy and robotic surgery. Multidisciplinary care is crucial for complex cases, improving outcomes through risk stratification, early detection, and tailored treatment strategies.

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Area of Science:

  • Hepatobiliary Medicine
  • Surgical Oncology
  • Immunotherapy

Background:

  • Hepatocellular carcinoma (HCC) management has undergone significant evolution.
  • Traditional treatment paradigms are expanding with new therapeutic modalities.

Purpose of the Study:

  • To provide a concise overview of current HCC management recommendations.
  • To highlight recent advances in systemic and surgical therapies for HCC.
  • To emphasize the importance of multidisciplinary approaches in HCC care.

Main Methods:

  • Review of recent clinical advancements in HCC treatment.
  • Analysis of immune-based therapies and surgical innovations.
  • Discussion of HCC downstaging strategies.

Main Results:

  • Immune-based treatments are now foundational for systemic HCC therapy.
  • Robotic surgery expands resection eligibility for selected HCC patients.
  • HCC downstaging offers comparable outcomes to conventional criteria.

Conclusions:

  • Modern HCC management is increasingly complex, requiring collaboration.
  • Shared decision-making is vital for optimal patient outcomes.
  • Practical recommendations cover risk stratification, detection, diagnosis, and treatment.