Related Experiment Video
Updated: Mar 27, 2026

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
Published on: December 23, 2013
Co-packaged electronics with microfluidics for direct-to-package cooling
Henry A Martin1,2,3, Zihan Zhang4, Mahad Saeed5,6
1Chip Integration Technology Center (CITC), Nijmegen, The Netherlands. henry.martin@tno.nl.
Abstract:
Power semiconductors operating under high heat fluxes and elevated temperatures rely on liquid-cooled heat sinks with substantial coolant volumes. Recent advancements in direct-to-chip (D2C) cooling techniques have shown enhanced thermal performance, reduced energy consumption, compact form factor, and minimized coolant usage. However, integrating microchannels onto semiconductor substrates poses significant fabrication challenges. Hence, we propose a direct-to-package (D2P) cooling approach that embeds microchannels within the package substrate, thereby bypassing the need for Thermal Interface Materials and complex fabrication processes. This D2P approach achieves high heat flux dissipation (up to ~ 625 W cm-2) tested in this study, while consuming a fraction of the coolant volume ( ~ 2 - 4 mL). The co-packaged architecture demonstrates ~ 6 - 7 × lower junction temperatures and thermal resistances than ambient-air cooling and ~ 2 - 3 × lower than heat sink cooling. A very high coefficient of performance is achieved, with an effective global Nusselt number > 10. This work establishes D2P liquid cooling integration as a scalable and energy-efficient approach for high-power systems.

