Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

DNA-Engineered Dual-Signal Biomimetic Fusion Vesicles for Rapid Evaluation of Systemic Lupus Erythematosus.

Analytical chemistry·2026

Same author

PRC1 impairs sepsis host defense by suppressing NF-κB/JAK-STAT signaling and macrophage glycolytic reprogramming.

International immunopharmacology·2026

Same author

Analysis of cholesterol-induced mechanical modulation of cell membranes by nanopipette-generated fluid flow.

The Analyst·2026

Same author

Pyrolysis temperature-driven structural evolution of wheat straw biochar and enhanced adsorption mechanisms for Cr(vi).

RSC advances·2026

Same author

Multiple accessory-genes sequence typing (MAST): pan-genome-guided PCR target discovery enables species-level discrimination in Salmonella surveillance.

FEMS microbiology letters·2026

Same author

Optoelectronic performance of anthracene-based dyes with modified Hagfeldt donors in dye-sensitized solar cells.

Physical chemistry chemical physics : PCCP·2026

Same journal

The Versatile Structural World of Methanedi- and Trisulfonic Acid and Their Salts.

ChemistryOpen·2026

Same journal

The Role of Conformational Preorganization in the Reactivity of cis-1,2-Dimesylate-bis(benzyloxy)cyclooctane: An Activation Strain Perspective.

ChemistryOpen·2026

Same journal

Epoxy Clerodane Diterpene Attenuates the Differentiated Adipocyte Hypertrophy and Enhances Mitochondrial Metabolism.

ChemistryOpen·2026

Same journal

Magnetic Nickel-Containing Heterogeneous Catalysts for the Heck Reaction: Catalyst Design, Performance, and Sustainability.

ChemistryOpen·2026

Same journal

First-Principles Design of Room Temperature Ferromagnetic Metallic Rare-Earth Zintl Compounds AB<sub>2</sub>C<sub>2</sub> (A = Ce, Pr, Nd; B = Li; C = Sb) for Next-Generation Spintronic and Magneto-Electronic Applications.

ChemistryOpen·2026

Same journal

Comparative Density Functional Theory Insights Into B<sub>16</sub>C<sub>16</sub> and Si<sub>16</sub>C<sub>16</sub> Nanocages for Sensing Oil-Derived Fault Gases in Energy and Industrial Systems.

ChemistryOpen·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 27, 2026

Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements

Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements

Published on: December 2, 2022

DNAzyme-Based Nanostructures for Dynamic Cell Regulation and Sensing.

Haoyu Fan¹, Xichen Du², Ruocan Qian²

¹International Elite Engineering School, East China University of Science and Technology, Shanghai, China.

|March 26, 2026

Summary

This summary is machine-generated.

DNAzyme nanostructures offer advanced cellular regulation and biosensing. Integrating DNAzymes with nanomaterials enhances stability and performance for applications in imaging, therapy, and diagnostics.

Keywords:

DNAzyme bioimaging biosensing cell regulation nanostructure

More Related Videos

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

Related Experiment Videos

Last Updated: Mar 27, 2026

Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements

Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements

Published on: December 2, 2022

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

Area of Science:

Biotechnology
Nanotechnology
Molecular Biology

Background:

DNAzymes are catalytic DNA molecules with high stability and programmability.
Traditional DNAzyme applications face limitations like nuclease susceptibility and poor cellular uptake.
Nanomaterial integration offers solutions to enhance DNAzyme performance in biological systems.

Purpose of the Study:

To review advancements in DNAzyme-based nanostructures for cellular regulation and biosensing.
To explore innovations in DNAzyme-nanomaterial integration for improved functionality.
To discuss the therapeutic and diagnostic potential of these advanced systems.

Main Methods:

Systematic review of cutting-edge research on DNAzyme nanostructures.
Analysis of DNAzyme integration with various nanomaterials (liposomes, gold nanoparticles, MOFs).
Discussion of key innovations like logic-gated systems, rRNA-activated sensors, and nanodevices.

Main Results:

DNAzyme-nanomaterial hybrids overcome limitations, showing enhanced stability and cellular uptake.
Novel applications include programmable cell assembly, subcellular imaging, and amplified biosensing.
DNAzyme nanostructures demonstrate potential in targeted gene silencing and cancer therapy.

Conclusions:

DNAzyme-based nanostructures represent a significant advancement in dynamic cellular regulation and biosensing.
These technologies hold promise for developing novel theranostic platforms and therapeutic strategies.
Future directions focus on clinical translation through context-responsive and biocompatible designs.