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Establishing and Managing a Biobank at an Academic Institution in a Resource-Limited Setting: A Case Study from
Alexander Maldonado1,2,3, Andrés Herrera-Yela1,2,3, Evaluna Chicango1
1Biomedical Sciences, Health Sciences Faculty, Universidad Internacional SEK (UISEK), Quito, Ecuador.
Introduction:
Advances in technology and scientific research have enabled the establishment of biobanks worldwide, starting as centers for storing biological samples and evolving into institutions with specialized infrastructure. Establishing a biobank in an academic institution with limited resources is often considered a difficult goal. However, at Universidad Internacional SEK in Quito, Ecuador, this challenge has been seen as an opportunity to establish a biobank without external funding or specialized infrastructure.
Materials And Methods:
A descriptive case study design was used to document the establishment process. For ease of use, microbial isolates were used to implement workflows; these were obtained from undergraduate teaching laboratories and through formal collaboration with a clinical laboratory. The biobank was developed under a quality management system in accordance with International Organization for Standardization (ISO) 20387, including the creation of standard operating procedures (SOPs) and governance documents. Performance indicators were established, such as sample storage capacity, processing time, SOP compliance, viability rate, and readiness for the future integration of clinical samples.
Results:
A total of 190 biological samples were incorporated, including 46 bacterial isolates obtained during teaching practice and 144 diverse microorganisms, including multidrug-resistant strains, provided by the collaborating laboratory. Twenty-five initial SOPs were developed. Storage capacity reached 80%, with an average processing time of 2.5 hours per sample. Viability tests confirmed a 96% recovery rate after 3 months of storage. Student participation in the project provided training in biosafety, traceability, and quality management. Human samples were not included at this stage, as the objective was to establish ethical and legal frameworks that would allow for future expansion.
Conclusion:
This case study demonstrates that the implementation of biobanks in low- and middle-income countries is viable and operational and strengthens the academic system by integrating teaching and research toward a sustainable scientific infrastructure.
