Related Experiment Video
Updated: Mar 27, 2026

Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice
Published on: February 10, 2013
Exercise stress cardiomyopathy-a case report
Penni L Russell1, Joshua Martin1, Michael J Dwan1
1Department of Cardiology, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia.
Background:
Stress cardiomyopathy (Takotsubo syndrome) is a characteristically reversible cardiomyopathy with several potential triggers. The condition has been described in the context of stress echocardiography, particularly following the use of pharmacological agents such as dobutamine. The association between Takotsubo syndrome and exercise stress echocardiography is less commonly reported.
Case Summary:
Exercise stress echocardiography was utilized in the investigation of dyspnoea in a 62-year-old female referred to the outpatient cardiology clinic. Inducible regional wall motion abnormalities were identified at peak stress, with associated ECG changes. Subsequent multimodality investigation, including cardiac magnetic resonance imaging, confirmed the diagnosis of stress cardiomyopathy, with coronary angiography revealing only minor coronary artery disease. Serial imaging was crucial in demonstrating complete resolution of the initial abnormalities, supporting the diagnosis.
Discussion:
Takotsubo syndrome during stress echocardiography is a rare occurrence, with relatively few cases having been described in the context of exercise stress testing. This case demonstrated echocardiographic findings that were similar to major ischaemia. A comprehensive multimodality approach was required to exclude significant coronary artery disease and confirm the diagnosis of exercise stress cardiomyopathy.
Related Concept Videos
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy I: Introduction and Classification
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis I: Introduction

