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Triboelectric nanogenerators for self-powered neurostimulation.
Shumao Xu1, Farid Manshaii1, Xiao Xiao1
1Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Nano Research
|March 26, 2026
Summary
Triboelectric nanogenerators (TENGs) offer a solution for self-powered neurostimulation devices, eliminating the need for batteries. This technology shows promise for advancing treatments for neurological and psychiatric conditions.
Area of Science:
- Soft bioelectronics
- Neuroscience
- Materials science
Background:
- Traditional batteries limit miniaturization and require invasive replacement for neurostimulation devices.
- Self-powered devices are crucial for advanced neurological and psychiatric treatments.
Purpose of the Study:
- To review recent advancements in triboelectric nanogenerators (TENGs) for self-powered neurostimulation.
- To explore the application of TENGs across central, autonomic, and somatic nervous systems.
- To discuss challenges and solutions for clinical translation of TENG-based neural devices.
Main Methods:
- Review of recent literature on TENGs in neurostimulation.
- Analysis of TENG operational principles and energy harvesting from biomechanical movements.
- Examination of neural electrode implantation and integration strategies.
Main Results:
- TENGs provide a viable alternative to traditional batteries for powering neurostimulation devices.
- Applications of TENGs span various neural systems, demonstrating broad therapeutic potential.
- Recent advances address challenges in neural electrode integration for improved clinical translation.
Conclusions:
- TENGs are a promising technology for self-powered, minimally invasive neurostimulation.
- Further development in electrode design and integration is key for widespread clinical adoption.
- TENGs have the potential to revolutionize the treatment of neurological diseases.
