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Sonidegib Therapy for Locally Advanced Basal Cell Carcinoma in an Elderly Patient: A Case Report
Yuyu Deng1,2,3,4,5, Pingxiu He1,2,3,4,5, Changxia Li1,2,3,4,5
1Dermatology Department, Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi, People's Republic of China.
Abstract:
We report a case of locally advanced basal cell carcinoma (BCC) of the nose successfully treated with oral sonidegib. An 87-year-old man presented with a pruritic brown papule in the right nasolabial fold, progressively enlarging for >10 years and ulcerated for 7 years. Histopathology confirmed nodular BCC with tumor thickness ≥6 mm. Sonidegib (200 mg daily) was initiated, and a complete resolution was achieved after 5 months. No recurrence or significant adverse effects were observed 4 months post-treatment.
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