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Updated: Mar 27, 2026
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Identifying Priority Outcomes for Mothers and Babies in Pregnancies With Preterm Pre-Labour Rupture of Membranes for
Ahalya Sathiyaselvan1,2, Lisa Dawes1,2, Nadia Olivier3
1Liggins Institute, University of Auckland, Auckland, New Zealand.
Abstract:
Preterm pre-labour rupture of membranes (PPROM) is associated with neonatal and maternal morbidity and mortality. Maternal prophylactic antibiotic therapy after PPROM improves outcomes but there is limited evidence to guide the optimal antibiotic regimen. This study surveyed 45 women with PPROM to understand consumer priorities for care, maternal and neonatal outcomes; and inform future PPROM clinical trial design. The highest priorities were prolonging gestation, avoiding brain injury, improving neonatal survival and good childhood respiratory health. Seventy-nine percent of respondents would consider clinical trial participation. Identifying consumer priorities will support both trial design and improved clinical care.
