Visual Analysis of Research Status and Trends in Relationship Between Circadian Rhythm and Obesity

Objective To analyze the research bases,research hotspots,and future research trends in the relationship between the circadian rhythm and obesity,thus providing a reference for research in this field. Methods Literature on obesity and circadian rhythm published from 2001 to June 2024 was retrieved from the Web of Science.CiteSpace and VOSviewer were used for scientometric analysis. Results This study included 1 185 publications from 4 083 organizations in 354 countries/regions.Annual number of publications in this field showed an overall upward trend,with particularly rapid growth after 2019.Countries such as the United States and Ireland exerted significant influence in this field.Keyword co-occurrence and cluster analysis identified adipose tissue and meal timing as closely related keywords.The burst analysis indicated gut microbiota and DNA methylation as current research hotspots. Conclusions The research on the association between circadian rhythm and obesity primarily centers on the interaction between circadian rhythm and gut microbiota,which influences lipid metabolism processes,and on the regulation of circadian rhythm through meal timing to reduce obesity risk.Incorporating epigenetics in the research on circadian rhythm and obesity may represent an important future research direction.