Related Experiment Video
Updated: Mar 27, 2026

08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.9K
Flap Use for Wound Coverage After Spinal Hardware Infection: A Systematic Review of the Literature
Marah I Jolibois1,2, Artur Manasyan3, Idean Roohani3
1Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, Los Angeles, California, USA.
Microsurgery
|March 26, 2026
Summary
Flap reconstruction effectively covers infected spinal defects, with muscle flaps showing higher survival rates (92%) than fasciocutaneous flaps (85%). This approach is vital for managing complex spinal wounds and improving patient outcomes.
Area of Science:
- Orthopedic Surgery
- Plastic Surgery
- Infectious Disease
Background:
- Spinal defects with surgical site infections (SSIs) are challenging, affecting 1%-4% of spine surgeries.
- SSIs often involve hardware exposure, increasing hospital stays, costs, and poor outcomes.
- Effective management of infected spinal wounds is critical.
Purpose of the Study:
- To systematically review flap reconstruction techniques for spinal defects with surgical site infections.
- To evaluate outcomes including flap survival, necrosis, dehiscence, and infection rates.
- To provide evidence-based insights for managing complex spinal wounds.
Main Methods:
- Systematic review following PRISMA-P guidelines across six databases.
- Included studies reported flap coverage for spinal reconstructions (with or without hardware).
- Quality assessed using ASPS criteria and ROBINS-I tool.
Main Results:
- 32 studies (969 patients) were included; 496 had reconstructions for infected chronic wounds.
- Staphylococcus aureus was the most common organism (52.7%). Paraspinal and latissimus dorsi flaps were most common.
- Pooled flap survival was 89%; muscle flaps (92%) outperformed fasciocutaneous flaps (85%). Complications included wound dehiscence (12%), flap necrosis (8%), and reinfection (10%).
Conclusions:
- Flap reconstruction is a viable solution for soft-tissue coverage in complex spinal defects.
- Muscle flaps demonstrate higher effectiveness compared to fasciocutaneous flaps.
- Tailored surgical planning based on defect and patient factors is essential for successful management.

