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Novel autoantibodies in autoimmune hepatitis: from diagnostic challenges to molecular and spatial pathology

Kazumichi Abe1, Jun Wada2, Manabu Hayashi2

  • 1Department of Gastroenterology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima City, Fukushima, 960-1295, Japan. k-abe@fmu.ac.jp.

Medical Molecular Morphology
|March 26, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AutoantibodyAutoimmune hepatitisDocking protein 2Human protein microarrayMacrophage

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
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Keywords:
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