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Updated: Mar 28, 2026

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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MAP2K6 directly phosphorylates BCL2L13 to mediate mitophagy for suppressing tumorigenicity

Guangsuo Xing1, Yile Huang2, Xiwen Liu3

  • 1Institute of Development and Regeneration, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, State Key Laboratory of Immune Response and Immunotherapy, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Cell Reports
|March 26, 2026
PubMed
Abstract

Keywords:
CP: cancerCP: metabolismOXPHOSautophagycancer metabolismmetabolismmitochondriamitophagy

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