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Related Experiment Video

Updated: Mar 28, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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Community Health Worker-Integrated Model for Sickle Cell Disease Management: Protocol for a Feasibility Study.

Tilicia Mayo-Gamble1, Doreen Ugwu1, Tobi Oloyede1

  • 1Health Policy and Community Health, Jiann-Ping Hsu College of Public Health, Georgia Southern University, 501 Forest Dr, Statesboro, GA, 30458, United States, 1 912-478-1249.

JMIR Research Protocols
|March 26, 2026
PubMed
Summary
This summary is machine-generated.

Integrating community health workers (CHWs) into sickle cell disease (SCD) management shows promise for improving care coordination and patient self-management. This study evaluates the feasibility and acceptability of this CHW-integrated model in adults with SCD.

Keywords:
community health workermixed methodspatient-centered careresearch protocolself-caresickle cell disease

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Area of Science:

  • Public Health
  • Health Services Research
  • Chronic Disease Management

Background:

  • Sickle cell disease (SCD) is a chronic inherited blood disorder impacting African Americans, presenting complex management challenges due to fragmented care.
  • Poor health outcomes and patient satisfaction are linked to the current care delivery model for SCD.

Purpose of the Study:

  • To test the feasibility and acceptability of a community health worker (CHW)-integrated model for managing sickle cell disease.
  • To enhance disease management and patient satisfaction through coordinated care.

Main Methods:

  • A multimethod study protocol evaluating an integrated CHW intervention for adults with SCD (aged 18-45).
  • Intervention includes CHW-led patient education and care coordination.
  • Quantitative outcomes (self-care behaviors, patient satisfaction) and qualitative data (semistructured interviews) will be collected.

Main Results:

  • Preliminary data on the impact of a CHW-integrated model on care coordination and self-management in adults with SCD.
  • 16 participants enrolled as of March 2026.

Conclusions:

  • Addresses a gap in literature by presenting a theory-informed, multimethod study protocol for CHW integration in SCD care.
  • Highlights a scalable, community-embedded strategy that may inform future clinical trials and implementation efforts for adults with SCD.