The Canadian Thoracic Society/Canadian Sleep Society Guideline on the Diagnosis of Obstructive Sleep Apnea in Children
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Published on: June 3, 2013
Joanna E MacLean1, Adetayo Adeleye2, Anne Van Dam3
1Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, AB, Canada.
Insights
Polysomnography remains the gold standard for diagnosing childhood obstructive sleep apnea (OSA). Home Sleep Apnea Testing is a recommended alternative for healthy children over 5 when polysomnography access is limited.
Area of Science:
- Pediatric Sleep Medicine
- Diagnostic Testing
- Respiratory Disorders
Background:
- Access to polysomnography (PSG), the standard for diagnosing obstructive sleep apnea (OSA) in children, is often limited.
- This leads to children being treated without confirmation, denied treatment, or experiencing delays in managing other sleep disorders.
Purpose of the Study:
- To systematically review and analyze alternative diagnostic methods for pediatric obstructive sleep apnea.
- To formulate evidence-based recommendations for OSA diagnosis in children, considering clinical evidence and patient preferences.
Main Methods:
- A systematic review and meta-analysis of 250 articles evaluating five types of clinical assessments for pediatric OSA.
- Recommendations were developed through an expert panel process involving proposal, discussion, revision, and voting.
Main Results:
- Most studies excluded children with comorbidities or did not report exclusions (62% and 26% respectively).
- Only 13% of included articles focused on children under two years of age, with limited data suitable for meta-analysis.
- Home Sleep Apnea Testing (Level 3) is recommended for healthy children over 5 years when PSG is unavailable.
Conclusions:
- Polysomnography is upheld as the definitive diagnostic standard for pediatric obstructive sleep apnea.
- Home Sleep Apnea Testing is a viable alternative for specific pediatric populations.
- Further development of accurate, accessible home-based testing is crucial, aligning with patient preferences.
Rationale:
Access to polysomnography, the recommended standard for the diagnosis of OSA in children, is limited in many jurisdictions. Many children undergo treatment for OSA without confirmatory testing, are denied treatment in the absence of testing, or have a delay in treatment of other sleep disorders until OSA can be ruled out.
Methods:
An expert panel conducted a systematic review and meta-analysis examining alternative testing to polysomnography. Recommendations formulation followed a process of proposal, discussion, revisions and voting, considering the evidence, panel members' judgment, as well as patient and family preferences.
Results:
A total of 250 articles across 5 types of clinical assessment were included. Most articles excluded children with comorbidities or did not report exclusions (62% and 26%, respectively). Only 13% of articles included children under 2-years of age. Limited data were appropriate for meta-analysis.
Conclusions:
The panel upholds polysomnography as the recommended standard for the diagnosis of OSA in children given the absence of an alternative test that could be considered a replacement. Level 3/Home Sleep Apnea Testing is recommended as an alternative option to diagnose OSA in otherwise healthy children over 5-years of age for whom access to polysomnography is effectively absent. While the Pediatric Sleep Questionnaire and overnight oximetry add information to the clinical assessment, we suggest that these should not be used to diagnose OSA in children. Given patient and family preferences for testing at home, further investment is needed in developing accurate and accessible home-based testing options to diagnose OSA in children.
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