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Updated: Mar 28, 2026

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
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Transcatheter Aortic Valve Explants: Calcification Patterns and Leaflet Thickening to Inform Repeat Interventions.

David Meier1, Joshua Yoon2, Cole Glenna3

  • 1Department of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Cardiovascular Translational Lab, Centre for Cardiovascular Innovation, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Heart Valve Innovation and Centre for Cardiovascular Innovation, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: http://twitter.com/david_meier_.

The Canadian Journal of Cardiology
|March 26, 2026
PubMed
Summary

Degeneration of transcatheter aortic valves (TAVs) is common. Explanted TAVs show calcification and thickening, with patterns varying by TAV type, impacting future interventions.

Keywords:
Transcatheter aortic valve replacementcalcificationdegenerationhistopathologyredo transcatheter aortic valve replacement

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