Related Experiment Video
Updated: Mar 28, 2026
04:05
Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
3.0K
Phase angle reference values derived from bioelectrical impedance analysis in chinese multi-ethnic adults
Zhiming Lu1,2, Yaoda Hu2,3, Huijing He2,3
1Precision and Intelligence Medical Imaging Lab, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Annals of Medicine
|March 26, 2026
Summary
This study establishes crucial age-, sex-, and ethnicity-specific reference values for Phase Angle (PhA) in Chinese adults. These findings, derived from bioelectrical impedance analysis, aid in assessing body composition and health status across diverse populations.
Area of Science:
- Biomedical Science
- Anthropometry
- Public Health
Background:
- Accurate reference values for body composition parameters are essential for clinical assessment.
- Phase Angle (PhA), a measure derived from bioelectrical impedance analysis (BIA), reflects cellular integrity and nutritional status.
- Existing PhA reference values lack specificity for diverse ethnic groups and age ranges in China.
Purpose of the Study:
- To develop age-, sex-, and ethnicity-specific reference values for Phase Angle (PhA) in Chinese adults.
- To provide a normative dataset for PhA using bioelectrical impedance analysis (BIA) in a large, diverse Chinese population.
- To facilitate improved clinical interpretation of PhA measurements.
Main Methods:
- A large-scale cross-sectional study involving 13,256 healthy Chinese adults (aged 20-80 years) from Han, Korean, and Yao ethnic groups.
- Phase Angle (PhA) was measured using bioelectrical impedance analysis (BIA) at 50 kHz.
- Generalized Additive Models for Location, Scale, and Shape (GAMLSS) were employed to establish percentile-specific reference values (5th to 95th).
Main Results:
- The study established comprehensive PhA reference ranges for men and women across different ethnicities and age groups.
- Peak PhA values in men were observed between 30-49 years, varying slightly by ethnicity, with a decline after 50 years.
- Women generally showed peak PhA values between 40-49 years, with consistently higher PhA values noted in men compared to women across all groups.
Conclusions:
- This research provides the first age-, sex-, and ethnicity-specific PhA reference values for Chinese adults.
- The derived BIA-based PhA reference values are valuable tools for enhancing diagnosis and prognosis in various health conditions.
- These normative data support the utility of PhA in clinical settings for a more precise assessment of body composition and health status.
