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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Risk Factor Analysis and Prognosis of Dysphagia in Craniocerebral Injury Patients: Implications for Targeted Nursing
Qingye Zhang1, Yuxia Pan1, Hongyi Sun2
1Intensive Care Unit, Taizhou Hospital of Traditional Chinese Medicine (Taizhou Affiliated Hospital of Nanjing University of Chinese Medicine), Taizhou, China.
Background:
This study aims to develop a predictive model for risk factors associated with dysphagia in patients with craniocerebral injury and to propose targeted nursing and rehabilitation interventions based on this model to improve patient outcomes.
Methods:
A retrospective analysis was conducted on clinical data from 150 patients with craniocerebral injury admitted between June 2022 and June 2024. Patients were divided into dysphagia (n = 62) and control (n = 88) groups based on the presence or absence of dysphagia. Univariate analysis and binary logistic regression were performed to identify independent risk factors for dysphagia, based on which a nomogram prediction model was subsequently constructed.
Results:
Binary logistic regression identified vagus nerve injury, tracheotomy/cannulation, mechanical ventilation, and severe aphasia as independent risk factors for dysphagia, while a higher Glasgow Coma Scale (GCS) score served as a protective factor. The nomogram model based on these variables demonstrated good predictive performance, with an AUC of 0.877 (95% CI: 0.823-0.931) as validated by internal bootstrap resampling. Decision curve analysis showed no significant difference between predicted and observed outcomes (X2 = 5.6728, p = 0.6838), and the absolute error between predicted and actual values was 0.038, indicating strong clinical utility.
Conclusion:
Vagus nerve injury, tracheotomy/cannulation, mechanical ventilation, severe aphasia, and GCS score are independent factors influencing the risk of dysphagia in craniocerebral injury patients. The developed predictive model demonstrates high accuracy and may provide a valuable reference for optimizing preventive nursing strategies and reducing the incidence of dysphagia.
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